NOTCH1 - LYN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
LYN	ENSG00000254087	No diseases in record	BOSUTINIB DASATINIB PONATINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity receptor binding platelet-derived growth factor receptor binding integrin binding protein binding ATP binding SH3 domain binding ubiquitin protein ligase binding gamma-tubulin binding glycosphingolipid binding ion channel binding phosphoprotein binding	Src64B (D. melanogaster)