NOTCH1 - DHFR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
DHFR	ENSG00000228716	No diseases in record	METHOTREXATE PEMETREXED PRALATREXATE	mRNA binding dihydrofolate reductase activity folic acid binding drug binding folate reductase activity methotrexate binding NADPH binding protein binding NADP binding	DFR1 (S. cerevisiae)