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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
Cancer:
Cancer gene:
Drug search:
Druggable:
Pathway:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
DLG3
ENSG00000082458
H. sapiens
guanylate kinase activity
protein binding
protein C-terminus binding
...
55
MLX
ENSG00000108788
H. sapiens
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
...
58
NR1H4
ENSG00000012504
H. sapiens
CHENODIOL
URSODIOL
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription factor binding
...
58
SNAI2
ENSG00000019549
H. sapiens
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
...
79
FLT4
ENSG00000037280
H. sapiens
soft tissue sarcoma
AXITINIB
LENVATINIB
NINTEDANIB
PAZOPANIB
REGORAFENIB
SORAFENIB
SUNITINIB
VANDETANIB
transmembrane receptor protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
protein binding
...
48
RNF167
ENSG00000108523
H. sapiens
ubiquitin-protein transferase activity
protein binding
zinc ion binding
...
77
BTK
ENSG00000010671
H. sapiens
CLL
mantle cell lymphoma
WM
IBRUTINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
...
273
ANAPC5
ENSG00000089053
H. sapiens
protein phosphatase binding
...
166
NOS1
ENSG00000089250
H. sapiens
nitric-oxide synthase activity
iron ion binding
protein binding
...
105
NLE1
ENSG00000073536
H. sapiens
...
24
MAP4
ENSG00000047849
H. sapiens
structural molecule activity
protein binding
microtubule binding
...
57
DNAJB6
ENSG00000105993
H. sapiens
ATPase activator activity
DNA binding
protein binding
...
121
SH3GLB1
ENSG00000097033
H. sapiens
protein binding
lipid binding
identical protein binding
...
94
SUFU
ENSG00000107882
H. sapiens
medulloblastoma
transcription corepressor activity
signal transducer activity
protein binding
...
137
KMT2C
ENSG00000055609
H. sapiens
medulloblastoma
DNA binding
protein binding
zinc ion binding
...
59
ELL
ENSG00000105656
H. sapiens
AL
protein binding
phosphatase binding
...
186
PUM2
ENSG00000055917
H. sapiens
RNA binding
mRNA 3'-UTR binding
protein binding
...
47
MYH9
ENSG00000100345
H. sapiens
ALCL
microfilament motor activity
motor activity
actin binding
...
107
GAB1
ENSG00000109458
H. sapiens
signal transducer activity
SH3/SH2 adaptor activity
protein binding
...
189
CDON
ENSG00000064309
H. sapiens
protein binding
...
54
EPHA3
ENSG00000044524
H. sapiens
lung cancer
CRC
melanoma
VANDETANIB
GPI-linked ephrin receptor activity
protein binding
ATP binding
...
22
TRIM9
ENSG00000100505
H. sapiens
SNARE binding
ubiquitin-protein transferase activity
protein binding
...
108
KLHL20
ENSG00000076321
H. sapiens
actin binding
ubiquitin-protein transferase activity
protein binding
...
68
EPB41L2
ENSG00000079819
H. sapiens
actin binding
structural constituent of cytoskeleton
spectrin binding
...
81
CBX7
ENSG00000100307
H. sapiens
chromatin binding
single-stranded RNA binding
protein binding
...
116
SPO11
ENSG00000054796
H. sapiens
DNA binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein binding
...
27
FGR
ENSG00000000938
H. sapiens
DASATINIB
phosphotyrosine residue binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
...
48
IPO11
ENSG00000086200
H. sapiens
protein binding
Ran GTPase binding
protein transporter activity
...
77
SCARB1
ENSG00000073060
H. sapiens
lipopolysaccharide binding
virus receptor activity
phosphatidylserine binding
...
68
SLC7A2
ENSG00000003989
H. sapiens
high-affinity arginine transmembrane transporter activity
high-affinity lysine transmembrane transporter activity
amino acid transmembrane transporter activity
...
60
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