POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101868 POLA1 ENSG00000173653 RCE1 H. sapiens SSL Slorth 0.937925 View
ENSG00000101868 POLA1 ENSG00000156802 ATAD2 H. sapiens SSL Slorth 0.937924 View
ENSG00000101868 POLA1 ENSG00000166974 MAPRE2 H. sapiens SSL Slorth 0.937854 View
ENSG00000101868 POLA1 ENSG00000130560 UBAC1 H. sapiens SSL Slorth 0.937849 View
ENSG00000101868 POLA1 ENSG00000198887 SMC5 H. sapiens SSL Slorth 0.937816 View
ENSG00000101868 POLA1 ENSG00000119414 PPP6C H. sapiens SSL Slorth 0.937694 View
ENSG00000101868 POLA1 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.937612 View
ENSG00000101868 POLA1 ENSG00000177879 AP3S1 H. sapiens SSL Slorth 0.937521 View
ENSG00000101868 POLA1 ENSG00000176105 YES1 H. sapiens SSL Slorth 0.937468 View
ENSG00000101868 POLA1 ENSG00000175931 UBE2O H. sapiens SSL Slorth 0.937427 View
ENSG00000101868 POLA1 ENSG00000213983 AP1G2 H. sapiens SSL Slorth 0.937408 View
ENSG00000101868 POLA1 ENSG00000117984 CTSD H. sapiens SSL Slorth 0.937403 View
ENSG00000101868 POLA1 ENSG00000171109 MFN1 H. sapiens SSL Slorth 0.937357 View
ENSG00000101868 POLA1 ENSG00000137825 ITPKA H. sapiens SDL Slorth 0.937348 View
ENSG00000101868 POLA1 ENSG00000115738 ID2 H. sapiens SSL Slorth 0.937334 View
ENSG00000101868 POLA1 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.93722 View
ENSG00000101868 POLA1 ENSG00000143878 RHOB H. sapiens SSL Slorth 0.93715 View
ENSG00000101868 POLA1 ENSG00000111300 NAA25 H. sapiens SSL Slorth 0.937074 View
ENSG00000101868 POLA1 ENSG00000108010 GLRX3 H. sapiens SSL Slorth 0.93705 View
ENSG00000101868 POLA1 ENSG00000140553 UNC45A H. sapiens SSL Slorth 0.937036 View
ENSG00000101868 POLA1 ENSG00000133884 DPF2 H. sapiens SSL Slorth 0.937 View
ENSG00000101868 POLA1 ENSG00000116141 MARK1 H. sapiens SSL Slorth 0.936995 View
ENSG00000101868 POLA1 ENSG00000168906 MAT2A H. sapiens SSL Slorth 0.936957 View
ENSG00000101868 POLA1 ENSG00000143344 RGL1 H. sapiens SDL Slorth 0.936922 View
ENSG00000101868 POLA1 ENSG00000159496 RGL4 H. sapiens SDL Slorth 0.936922 View
ENSG00000101868 POLA1 ENSG00000147130 ZMYM3 H. sapiens SSL Slorth 0.936837 View
ENSG00000101868 POLA1 ENSG00000180098 TRNAU1AP H. sapiens SSL Slorth 0.936748 View
ENSG00000101868 POLA1 ENSG00000140990 NDUFB10 H. sapiens SSL Slorth 0.936735 View
ENSG00000101868 POLA1 ENSG00000111481 COPZ1 H. sapiens SSL Slorth 0.936591 View
ENSG00000101868 POLA1 ENSG00000150779 TIMM8B H. sapiens SSL Slorth 0.936589 View
ENSG00000101868 POLA1 ENSG00000164690 SHH H. sapiens SSL Slorth 0.936446 View
ENSG00000101868 POLA1 ENSG00000117318 ID3 H. sapiens SSL Slorth 0.936437 View
ENSG00000101868 POLA1 ENSG00000142875 PRKACB H. sapiens SSL Slorth 0.936403 View
ENSG00000101868 POLA1 ENSG00000169100 SLC25A6 H. sapiens SSL Slorth 0.936287 View
ENSG00000101868 POLA1 ENSG00000124217 MOCS3 H. sapiens SSL Slorth 0.93609 View
ENSG00000101868 POLA1 ENSG00000129521 EGLN3 H. sapiens SSL Slorth 0.936059 View
ENSG00000101868 POLA1 ENSG00000113916 BCL6 H. sapiens SSL Slorth 0.936046 View
ENSG00000101868 POLA1 ENSG00000144566 RAB5A H. sapiens SSL Slorth 0.936042 View
ENSG00000101868 POLA1 ENSG00000179091 CYC1 H. sapiens SSL Slorth 0.936037 View
ENSG00000101868 POLA1 ENSG00000142273 CBLC H. sapiens SSL Slorth 0.936013 View