POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101868 POLA1 ENSG00000106976 DNM1 H. sapiens SSL Slorth 0.939243 View
ENSG00000101868 POLA1 ENSG00000109929 SC5D H. sapiens SSL Slorth 0.939228 View
ENSG00000101868 POLA1 ENSG00000174672 BRSK2 H. sapiens SSL Slorth 0.93918 View
ENSG00000101868 POLA1 ENSG00000163577 EIF5A2 H. sapiens SSL Slorth 0.939178 View
ENSG00000101868 POLA1 ENSG00000142655 PEX14 H. sapiens SSL Slorth 0.939171 View
ENSG00000101868 POLA1 ENSG00000173542 MOB1B H. sapiens SSL Slorth 0.93916 View
ENSG00000101868 POLA1 ENSG00000143569 UBAP2L H. sapiens SSL Slorth 0.939096 View
ENSG00000101868 POLA1 ENSG00000108946 PRKAR1A H. sapiens SSL Slorth 0.939059 View
ENSG00000084676 NCOA1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.939059 View
ENSG00000101868 POLA1 ENSG00000176248 ANAPC2 H. sapiens SSL Slorth 0.939034 View
ENSG00000101868 POLA1 ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.939008 View
ENSG00000101868 POLA1 ENSG00000126858 RHOT1 H. sapiens SSL Slorth 0.939006 View
ENSG00000101868 POLA1 ENSG00000108963 DPH1 H. sapiens SSL Slorth 0.93896 View
ENSG00000101868 POLA1 ENSG00000115758 ODC1 H. sapiens SSL Slorth 0.938952 View
ENSG00000101868 POLA1 ENSG00000155366 RHOC H. sapiens SSL Slorth 0.938933 View
ENSG00000101868 POLA1 ENSG00000154710 RABGEF1 H. sapiens SSL Slorth 0.938903 View
ENSG00000101868 POLA1 ENSG00000138756 BMP2K H. sapiens SDL Slorth 0.938856 View
ENSG00000101868 POLA1 ENSG00000171105 INSR H. sapiens SSL Slorth 0.938829 View
ENSG00000101868 POLA1 ENSG00000119314 PTBP3 H. sapiens SSL Slorth 0.938815 View
ENSG00000101868 POLA1 ENSG00000125354 SEPT6 H. sapiens SSL Slorth 0.938795 View
ENSG00000101868 POLA1 ENSG00000142949 PTPRF H. sapiens SSL Slorth 0.938787 View
ENSG00000101868 POLA1 ENSG00000177731 FLII H. sapiens SSL Slorth 0.938782 View
ENSG00000101868 POLA1 ENSG00000157087 ATP2B2 H. sapiens SSL Slorth 0.938757 View
ENSG00000101868 POLA1 ENSG00000173402 DAG1 H. sapiens SSL Slorth 0.938679 View
ENSG00000101868 POLA1 ENSG00000119689 DLST H. sapiens SSL Slorth 0.938664 View
ENSG00000101868 POLA1 ENSG00000215021 PHB2 H. sapiens SSL Slorth 0.938606 View
ENSG00000101868 POLA1 ENSG00000105968 H2AFV H. sapiens SSL Slorth 0.938587 View
ENSG00000101868 POLA1 ENSG00000167461 RAB8A H. sapiens SSL Slorth 0.938561 View
ENSG00000101868 POLA1 ENSG00000138071 ACTR2 H. sapiens SSL Slorth 0.938533 View
ENSG00000101868 POLA1 ENSG00000154928 EPHB1 H. sapiens SSL Slorth 0.938473 View
ENSG00000101868 POLA1 ENSG00000144744 UBA3 H. sapiens SSL Slorth 0.938455 View
ENSG00000101868 POLA1 ENSG00000134014 ELP3 H. sapiens SSL Slorth 0.938435 View
ENSG00000101868 POLA1 ENSG00000106367 AP1S1 H. sapiens SSL Slorth 0.938402 View
ENSG00000101868 POLA1 ENSG00000160867 FGFR4 H. sapiens SSL Slorth 0.938299 View
ENSG00000101868 POLA1 ENSG00000115306 SPTBN1 H. sapiens SSL Slorth 0.938185 View
ENSG00000101868 POLA1 ENSG00000116747 TROVE2 H. sapiens SSL Slorth 0.938142 View
ENSG00000101868 POLA1 ENSG00000205302 SNX2 H. sapiens SSL Slorth 0.938065 View
ENSG00000101868 POLA1 ENSG00000165699 TSC1 H. sapiens SSL Slorth 0.938045 View
ENSG00000101868 POLA1 ENSG00000122218 COPA H. sapiens SSL Slorth 0.93802 View
ENSG00000101868 POLA1 ENSG00000184009 ACTG1 H. sapiens SSL Slorth 0.937978 View