POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101868 POLA1 ENSG00000169439 SDC2 H. sapiens SSL Slorth 0.947514 View
ENSG00000101868 POLA1 ENSG00000163902 RPN1 H. sapiens SSL Slorth 0.94747 View
ENSG00000101868 POLA1 ENSG00000130429 ARPC1B H. sapiens SSL Slorth 0.947369 View
ENSG00000101868 POLA1 ENSG00000138758 SEPT11 H. sapiens SSL Slorth 0.947361 View
ENSG00000101868 POLA1 ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.947329 View
ENSG00000101868 POLA1 ENSG00000244038 DDOST H. sapiens SSL Slorth 0.947304 View
ENSG00000101868 POLA1 ENSG00000198719 DLL1 H. sapiens SSL Slorth 0.947267 View
ENSG00000101868 POLA1 ENSG00000125107 CNOT1 H. sapiens SSL Slorth 0.947267 View
ENSG00000101868 POLA1 ENSG00000153107 ANAPC1 H. sapiens SSL Slorth 0.947262 View
ENSG00000101868 POLA1 ENSG00000126934 MAP2K2 H. sapiens SSL Slorth 0.947221 View
ENSG00000101868 POLA1 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.947195 View
ENSG00000101868 POLA1 ENSG00000197579 TOPORS H. sapiens SSL Slorth 0.947156 View
ENSG00000101868 POLA1 ENSG00000106799 TGFBR1 H. sapiens SSL Slorth 0.94713 View
ENSG00000101868 POLA1 ENSG00000112742 TTK H. sapiens SSL Slorth 0.947111 View
ENSG00000101868 POLA1 ENSG00000175203 DCTN2 H. sapiens SSL Slorth 0.947101 View
ENSG00000101868 POLA1 ENSG00000141378 PTRH2 H. sapiens SSL Slorth 0.947096 View
ENSG00000101868 POLA1 ENSG00000132906 CASP9 H. sapiens SSL Slorth 0.947056 View
ENSG00000101868 POLA1 ENSG00000172115 CYCS H. sapiens SSL Slorth 0.947047 View
ENSG00000101868 POLA1 ENSG00000139719 VPS33A H. sapiens SSL Slorth 0.947016 View
ENSG00000101868 POLA1 ENSG00000123349 PFDN5 H. sapiens SSL Slorth 0.946978 View
ENSG00000101868 POLA1 ENSG00000130725 UBE2M H. sapiens SSL Slorth 0.946953 View
ENSG00000101868 POLA1 ENSG00000117395 EBNA1BP2 H. sapiens SSL Slorth 0.946919 View
ENSG00000101868 POLA1 ENSG00000183495 EP400 H. sapiens SSL Slorth 0.94691 View
ENSG00000101868 POLA1 ENSG00000115760 BIRC6 H. sapiens SSL Slorth 0.946851 View
ENSG00000101868 POLA1 ENSG00000169083 AR H. sapiens SSL Slorth 0.946823 View
ENSG00000101868 POLA1 ENSG00000126226 PCID2 H. sapiens SSL Slorth 0.946823 View
ENSG00000101868 POLA1 ENSG00000138468 SENP7 H. sapiens SDL Slorth 0.946808 View
ENSG00000101868 POLA1 ENSG00000154473 BUB3 H. sapiens SSL Slorth 0.946715 View
ENSG00000101868 POLA1 ENSG00000112282 MED23 H. sapiens SSL Slorth 0.946707 View
ENSG00000096384 HSP90AB1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.946672 View
ENSG00000101868 POLA1 ENSG00000151348 EXT2 H. sapiens SSL Slorth 0.946659 View
ENSG00000101868 POLA1 ENSG00000181090 EHMT1 H. sapiens SSL Slorth 0.946649 View
ENSG00000101868 POLA1 ENSG00000154997 SEPT14 H. sapiens SDL Slorth 0.946592 View
ENSG00000101868 POLA1 ENSG00000103549 RNF40 H. sapiens SSL Slorth 0.946589 View
ENSG00000101868 POLA1 ENSG00000134684 YARS H. sapiens SSL Slorth 0.946588 View
ENSG00000101868 POLA1 ENSG00000213585 VDAC1 H. sapiens SSL Slorth 0.946486 View
ENSG00000101868 POLA1 ENSG00000163558 PRKCI H. sapiens SSL Slorth 0.946477 View
ENSG00000101868 POLA1 ENSG00000127022 CANX H. sapiens SSL Slorth 0.946444 View
ENSG00000101868 POLA1 ENSG00000117758 STX12 H. sapiens SSL Slorth 0.946314 View
ENSG00000101868 POLA1 ENSG00000169189 NSMCE1 H. sapiens SSL Slorth 0.946261 View