ALK

ENSG00000171094 - H. sapiens

Pathways

Go term Description
GO:0004704 NF-kappaB-inducing kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042802 identical protein binding

Drugs

Drug name Description
CERITINIB ALK tyrosine kinase receptor inhibitor
CRIZOTINIB Hepatocyte growth factor receptor inhibitor

Diseases

Disease Name
ALCL
NSCLC
neuroblastoma
inflammatory myofibroblastic tumour
Spitzoid tumour

Orthologs

Gene Organism
scd-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000110092 CCND1 ENSG00000171094 ALK H. sapiens SDL Slorth 0.924184 View
ENSG00000108424 KPNB1 ENSG00000171094 ALK H. sapiens SDL Slorth 0.923433 View
ENSG00000107643 MAPK8 ENSG00000171094 ALK H. sapiens SDL Slorth 0.922086 View
ENSG00000130939 UBE4B ENSG00000171094 ALK H. sapiens SDL Slorth 0.920392 View
ENSG00000136997 MYC ENSG00000171094 ALK H. sapiens SSL Slorth 0.919697 View
ENSG00000100029 PES1 ENSG00000171094 ALK H. sapiens SDL Slorth 0.919083 View
ENSG00000131759 RARA ENSG00000171094 ALK H. sapiens SDL Slorth 0.917883 View
ENSG00000004897 CDC27 ENSG00000171094 ALK H. sapiens SDL Slorth 0.917082 View
ENSG00000117399 CDC20 ENSG00000171094 ALK H. sapiens SDL Slorth 0.915615 View
ENSG00000109971 HSPA8 ENSG00000171094 ALK H. sapiens SSL Slorth 0.914867 View
ENSG00000078747 ITCH ENSG00000171094 ALK H. sapiens SDL Slorth 0.910902 View
ENSG00000163930 BAP1 ENSG00000171094 ALK H. sapiens SDL Slorth 0.91089 View
ENSG00000142534 RPS11 ENSG00000171094 ALK H. sapiens SDL Slorth 0.910273 View
ENSG00000168148 HIST3H3 ENSG00000171094 ALK H. sapiens SDL Slorth 0.91023 View
ENSG00000130726 TRIM28 ENSG00000171094 ALK H. sapiens SDL Slorth 0.910106 View
ENSG00000108953 YWHAE ENSG00000171094 ALK H. sapiens SDL Slorth 0.910103 View
ENSG00000012048 BRCA1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.9098 View
ENSG00000064012 CASP8 ENSG00000171094 ALK H. sapiens SDL Slorth 0.907057 View
ENSG00000136930 PSMB7 ENSG00000171094 ALK H. sapiens SDL Slorth 0.90527 View
ENSG00000154229 PRKCA ENSG00000171094 ALK H. sapiens SDL Slorth 0.902843 View
ENSG00000110330 BIRC2 ENSG00000171094 ALK H. sapiens SDL Slorth 0.900552 View
ENSG00000133316 WDR74 ENSG00000171094 ALK H. sapiens SSL Slorth 0.897632 View
ENSG00000166913 YWHAB ENSG00000171094 ALK H. sapiens SSL Slorth 0.897171 View
ENSG00000117133 RPF1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.895744 View
ENSG00000108443 RPS6KB1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.88901 View
ENSG00000170312 CDK1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.887776 View
ENSG00000101868 POLA1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.887461 View
ENSG00000105974 CAV1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.884848 View
ENSG00000167552 TUBA1A ENSG00000171094 ALK H. sapiens SSL Slorth 0.884129 View
ENSG00000164924 YWHAZ ENSG00000171094 ALK H. sapiens SSL Slorth 0.883298 View
ENSG00000142192 APP ENSG00000171094 ALK H. sapiens SSL Slorth 0.880388 View
ENSG00000169083 AR ENSG00000171094 ALK H. sapiens SSL Slorth 0.879385 View
ENSG00000110713 NUP98 ENSG00000171094 ALK H. sapiens SSL Slorth 0.879355 View
ENSG00000127022 CANX ENSG00000171094 ALK H. sapiens SSL Slorth 0.878097 View
ENSG00000134308 YWHAQ ENSG00000171094 ALK H. sapiens SSL Slorth 0.87573 View
ENSG00000112062 MAPK14 ENSG00000171094 ALK H. sapiens SSL Slorth 0.875454 View
ENSG00000171094 ALK ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.875433 View
ENSG00000114767 RRP9 ENSG00000171094 ALK H. sapiens SSL Slorth 0.871891 View
ENSG00000049759 NEDD4L ENSG00000171094 ALK H. sapiens SSL Slorth 0.871824 View
ENSG00000102882 MAPK3 ENSG00000171094 ALK H. sapiens SSL Slorth 0.871758 View