ITCH - ALK

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITCH	ENSG00000078747	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding ubiquitin-like protein transferase activity ribonucleoprotein complex binding CXCR chemokine receptor binding ubiquitin protein ligase activity	RSP5 (S. cerevisiae) wwp-1 (C. elegans) Su(dx) (D. melanogaster)
ALK	ENSG00000171094	ALCL NSCLC neuroblastoma inflammatory myofibroblastic tumour Spitzoid tumour	CERITINIB CRIZOTINIB	NF-kappaB-inducing kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity protein binding ATP binding identical protein binding	scd-2 (C. elegans)