CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000149100 EIF3M H. sapiens SSL Slorth 0.805339 View
ENSG00000135446 CDK4 ENSG00000196367 TRRAP H. sapiens SSL Slorth 0.805271 View
ENSG00000135446 CDK4 ENSG00000167258 CDK12 H. sapiens SSL Slorth 0.805184 View
ENSG00000135446 CDK4 ENSG00000143867 OSR1 H. sapiens SSL Slorth 0.804888 View
ENSG00000102554 KLF5 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.804606 View
ENSG00000135446 CDK4 ENSG00000164597 COG5 H. sapiens SSL Slorth 0.804581 View
ENSG00000135446 CDK4 ENSG00000176749 CDK5R1 H. sapiens SSL Slorth 0.80414 View
ENSG00000135446 CDK4 ENSG00000255112 CHMP1B H. sapiens SSL Slorth 0.804023 View
ENSG00000135446 CDK4 ENSG00000178573 MAF H. sapiens SSL Slorth 0.804014 View
ENSG00000135446 CDK4 ENSG00000205250 E2F4 H. sapiens SSL Slorth 0.803335 View
ENSG00000135446 CDK4 ENSG00000183853 KIRREL H. sapiens SSL Slorth 0.803114 View
ENSG00000135446 CDK4 ENSG00000198836 OPA1 H. sapiens SSL Slorth 0.803037 View
ENSG00000078304 PPP2R5C ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.802637 View
ENSG00000135446 CDK4 ENSG00000149823 VPS51 H. sapiens SSL Slorth 0.802408 View
ENSG00000135446 CDK4 ENSG00000198890 PRMT6 H. sapiens SSL Slorth 0.802361 View
ENSG00000044115 CTNNA1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.80235 View
ENSG00000135446 CDK4 ENSG00000136158 SPRY2 H. sapiens SSL Slorth 0.802076 View
ENSG00000076604 TRAF4 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.802002 View
ENSG00000135446 CDK4 ENSG00000138071 ACTR2 H. sapiens SSL Slorth 0.801785 View
ENSG00000105329 TGFB1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.801457 View
ENSG00000135446 CDK4 ENSG00000170776 AKAP13 H. sapiens SSL Slorth 0.801439 View
ENSG00000101972 STAG2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.801196 View
ENSG00000113460 BRIX1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.801005 View
ENSG00000135446 CDK4 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.800406 View
ENSG00000135446 CDK4 ENSG00000154611 PSMA8 H. sapiens SSL Slorth 0.800027 View
ENSG00000122958 VPS26A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.799898 View
ENSG00000135446 CDK4 ENSG00000155111 CDK19 H. sapiens SSL Slorth 0.799882 View
ENSG00000135446 CDK4 ENSG00000182872 RBM10 H. sapiens SSL Slorth 0.799536 View
ENSG00000135446 CDK4 ENSG00000178028 DMAP1 H. sapiens SSL Slorth 0.798601 View
ENSG00000135446 CDK4 ENSG00000151923 TIAL1 H. sapiens SSL Slorth 0.798557 View
ENSG00000105221 AKT2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.798434 View
ENSG00000135446 CDK4 ENSG00000158092 NCK1 H. sapiens SSL Slorth 0.797523 View
ENSG00000135446 CDK4 ENSG00000135766 EGLN1 H. sapiens SSL Slorth 0.797506 View
ENSG00000135446 CDK4 ENSG00000137270 GCM1 H. sapiens SSL Slorth 0.797216 View
ENSG00000133226 SRRM1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.79708 View
ENSG00000115694 STK25 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.796841 View
ENSG00000135446 CDK4 ENSG00000149930 TAOK2 H. sapiens SSL Slorth 0.796744 View
ENSG00000070770 CSNK2A2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.796712 View
ENSG00000135446 CDK4 ENSG00000204301 NOTCH4 H. sapiens SSL Slorth 0.796579 View
ENSG00000135446 CDK4 ENSG00000136875 PRPF4 H. sapiens SSL Slorth 0.796471 View