TOP2A - HSPD1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
HSPD1	ENSG00000144381	No diseases in record	No drugs in record	lipopolysaccharide binding p53 binding DNA replication origin binding single-stranded DNA binding double-stranded RNA binding protein binding ATP binding ATPase activity ubiquitin protein ligase binding unfolded protein binding chaperone binding	HSP60 (S. cerevisiae) hsp-60 (C. elegans) Hsp60C (D. melanogaster)