SPT15 - HST1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SPT15	YER148W	No diseases in record	No drugs in record	DNA binding RNA polymerase II activating transcription factor binding transcription factor activity, RNA polymerase I transcription factor recruiting RNA polymerase I transcription factor binding RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly chromatin binding DNA binding, bending TFIIIB-type transcription factor activity RNA polymerase III regulatory region DNA binding sequence-specific DNA binding	TBPL1 (H. sapiens) TBP (H. sapiens) TBPL2 (H. sapiens)
HST1	YOL068C	No diseases in record	No drugs in record	hydrolase activity NAD-dependent histone deacetylase activity NAD-independent histone deacetylase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides zinc ion binding NAD binding NAD+ binding metal ion binding	SIRT1 (H. sapiens)