SIR2 - SPT5

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
SPT5	YML010W	No diseases in record	No drugs in record	single-stranded RNA binding mRNA binding transcription factor activity, core RNA polymerase II binding RNA polymerase II core binding protein complex binding RNA polymerase I transcription factor binding RNA polymerase I core binding rRNA binding transcription factor activity, core RNA polymerase I binding protein heterodimerization activity protein binding	SUPT5H (H. sapiens)