SIR2 - ROM2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
ROM2	YLR371W	No diseases in record	No drugs in record	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity phosphatidylinositol-4,5-bisphosphate binding signal transducer activity	ARHGEF1 (H. sapiens) ARHGEF2 (H. sapiens) ARHGEF11 (H. sapiens) AKAP13 (H. sapiens) ARHGEF3 (H. sapiens) ARHGEF12 (H. sapiens) NET1 (H. sapiens) ARHGEF28 (H. sapiens)