SIR2 - RAD2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
RAD2	YGR258C	No diseases in record	No drugs in record	single-stranded DNA endodeoxyribonuclease activity hydrolase activity hydrolase activity, acting on ester bonds nuclease activity endonuclease activity metal ion binding DNA binding single-stranded DNA binding catalytic activity protein binding single-stranded DNA 5'-3' exodeoxyribonuclease activity double-stranded DNA 5'-3' exodeoxyribonuclease activity 5'-flap endonuclease activity 5'-3' exodeoxyribonuclease activity involved in UV-damage excision repair	ERCC5 (H. sapiens)