SIR2 - POL3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
POL3	YDL102W	No diseases in record	No drugs in record	3'-5'-exodeoxyribonuclease activity DNA-directed DNA polymerase activity 3'-5' exonuclease activity nucleotide binding DNA binding nucleotidyltransferase activity hydrolase activity metal ion binding exonuclease activity 4 iron, 4 sulfur cluster binding iron-sulfur cluster binding transferase activity nuclease activity nucleic acid binding	POLD1 (H. sapiens)