SIR2 - GCN5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
GCN5	YGR252W	No diseases in record	No drugs in record	N-acetyltransferase activity histone acetyltransferase activity transferase activity, transferring acyl groups H3 histone acetyltransferase activity transferase activity lysine-acetylated histone binding transcription coactivator activity protein binding chromatin binding H4 histone acetyltransferase activity	BAZ1A (H. sapiens) BAZ2A (H. sapiens) KAT2B (H. sapiens) KAT2A (H. sapiens) BPTF (H. sapiens) CECR2 (H. sapiens)