SIR2 - DST1

S. cerevisiae

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SIR2 YDL042C

No diseases in record

No drugs in record

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NAD-dependent histone deacetylase activity
NAD-dependent histone deacetylase activity (H3-K14 specific)
hydrolase activity
nucleosome binding
zinc ion binding
NAD binding
NAD+ binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
histone deacetylase activity (H3-K4 specific)
histone deacetylase activity (H3-K9 specific)
histone deacetylase activity
histone deacetylase activity (H4-K16 specific)
histone deacetylase activity (H3-K14 specific)
SIRT1 (H. sapiens)
DST1 YGL043W

No diseases in record

No drugs in record

metal ion binding
transcription factor activity, core RNA polymerase II recruiting
RNA polymerase II regulatory region DNA binding
RNA polymerase II core binding
nucleic acid binding
DNA binding
zinc ion binding
TCEA2 (H. sapiens)
TCEA1 (H. sapiens)