TOP2A - CARM1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
CARM1	ENSG00000142453	No diseases in record	No drugs in record	transcription coactivator activity protein binding beta-catenin binding protein methyltransferase activity histone-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity ligand-dependent nuclear receptor transcription coactivator activity protein-arginine omega-N asymmetric methyltransferase activity histone methyltransferase activity (H3-R17 specific) histone methyltransferase activity protein homodimerization activity transcription regulatory region DNA binding lysine-acetylated histone binding	HMT1 (S. cerevisiae) Art4 (D. melanogaster)