HHT1 - SIR2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HHT1	YBR010W	No diseases in record	No drugs in record	DNA binding protein heterodimerization activity nucleosomal DNA binding protein binding	H3F3B (H. sapiens) H3F3A (H. sapiens) HIST3H3 (H. sapiens) HIST1H3J (H. sapiens) HIST2H3D (H. sapiens) H3F3C (H. sapiens) HIST1H2AE (H. sapiens) HIST1H3D (H. sapiens) HIST1H3H (H. sapiens)
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)