SMAD5 - CDK4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD5	ENSG00000113658	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding signal transducer activity, downstream of receptor protein binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding metal ion binding	sma-3 (C. elegans) sma-2 (C. elegans)
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)