PDGFRA - H3F3A

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PDGFRA ENSG00000134853 GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma
BECAPLERMIN
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
REGORAFENIB
SUNITINIB
protein kinase activity
transmembrane receptor protein tyrosine kinase activity
platelet-derived growth factor alpha-receptor activity
vascular endothelial growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
platelet-derived growth factor receptor binding
protein binding
ATP binding
vascular endothelial growth factor binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding
Pvr (D. melanogaster)
H3F3A ENSG00000163041 glioma

No drugs in record

RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
protein binding
nucleosomal DNA binding
histone binding
protein heterodimerization activity
HHT1 (S. cerevisiae)
HHT2 (S. cerevisiae)