PDGFRA - ATM

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PDGFRA ENSG00000134853 GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma
BECAPLERMIN
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
REGORAFENIB
SUNITINIB
protein kinase activity
transmembrane receptor protein tyrosine kinase activity
platelet-derived growth factor alpha-receptor activity
vascular endothelial growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
platelet-derived growth factor receptor binding
protein binding
ATP binding
vascular endothelial growth factor binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding
Pvr (D. melanogaster)
ATM ENSG00000149311 T-PLL
leukaemia
lymphoma
medulloblastoma
glioma

No drugs in record

DNA binding
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
protein complex binding
protein dimerization activity
protein N-terminus binding
TEL1 (S. cerevisiae)
tefu (D. melanogaster)