KRAS - LCK

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KRAS	ENSG00000133703	pancreatic colorectal lung thyroid AML other tumour types	No drugs in record	GTPase activity protein binding GTP binding GMP binding GDP binding LRR domain binding protein complex binding	RAS1 (S. cerevisiae) RAS2 (S. cerevisiae) let-60 (C. elegans) Ras85D (D. melanogaster)
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)