BRCA2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRCA2	ENSG00000139618	breast ovarian pancreatic leukaemia	No drugs in record	protease binding single-stranded DNA binding protein binding protein C-terminus binding H3 histone acetyltransferase activity H4 histone acetyltransferase activity gamma-tubulin binding histone acetyltransferase activity	No GO terms in record
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)