SIRT1 - UBA2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
UBA2	ENSG00000126261	No diseases in record	No drugs in record	protein binding ATP binding enzyme activator activity transcription factor binding SUMO activating enzyme activity metal ion binding protein heterodimerization activity nucleotide binding ligase activity small protein activating enzyme activity ubiquitin activating enzyme binding	UBA2 (S. cerevisiae) uba-2 (C. elegans) Uba2 (D. melanogaster)