PIK3CA - SKI

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIK3CA	ENSG00000121879	colorectal gastric glioblastoma breast	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding kinase activity 1-phosphatidylinositol-3-kinase activity protein kinase activator activity phosphatidylinositol 3-kinase activity 1-phosphatidylinositol-4-phosphate 3-kinase activity insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	VPS34 (S. cerevisiae)
SKI	ENSG00000157933	melanoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription corepressor activity protein binding zinc ion binding protein kinase binding protein domain specific binding ubiquitin protein ligase binding SMAD binding histone deacetylase inhibitor activity repressing transcription factor binding	Snoo (D. melanogaster)