PIK3CA - CHEK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIK3CA	ENSG00000121879	colorectal gastric glioblastoma breast	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding kinase activity 1-phosphatidylinositol-3-kinase activity protein kinase activator activity phosphatidylinositol 3-kinase activity 1-phosphatidylinositol-4-phosphate 3-kinase activity insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	VPS34 (S. cerevisiae)
CHEK2	ENSG00000183765	breast	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding protein kinase binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity metal ion binding	RAD53 (S. cerevisiae) chk-2 (C. elegans) T08D2.7 (C. elegans) lok (D. melanogaster)