PIM1 - SMAD4

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIM1	ENSG00000137193	NHL	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding transcription factor binding manganese ion binding ribosomal small subunit binding mitochondrial light strand promoter anti-sense binding serine-type peptidase activity ATP-dependent peptidase activity nucleotide binding peptidase activity single-stranded DNA binding serine-type endopeptidase activity hydrolase activity DNA binding Ran guanyl-nucleotide exchange factor activity	PSK1 (S. cerevisiae) PSK2 (S. cerevisiae)
SMAD4	ENSG00000141646	colorectal pancreatic small intestine gastrointestinal polyp	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding chromatin binding protein binding collagen binding transforming growth factor beta receptor, common-partner cytoplasmic mediator activity identical protein binding protein homodimerization activity transcription regulatory region DNA binding metal ion binding protein heterodimerization activity I-SMAD binding R-SMAD binding transcription factor activity, protein binding DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding	Med (D. melanogaster)