COPS5 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
COPS5	ENSG00000121022	No diseases in record	No drugs in record	transcription coactivator activity translation initiation factor activity thiol-dependent ubiquitin-specific protease activity protein binding metallopeptidase activity metal ion binding	RRI1 (S. cerevisiae) CSN5 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)