TSC2 - PTEN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TSC2	ENSG00000103197	pulmonary lymphangioleiomyomatosis renal angiomyolipoma HNSCC hamartoma renal cell carcinoma tuberous sclerosis tuber	No drugs in record	GTPase activator activity protein binding phosphatase binding small GTPase binding protein homodimerization activity	No GO terms in record
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)