KMT2A - SMAD1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KMT2A	ENSG00000118058	AML ALL	No drugs in record	core promoter sequence-specific DNA binding AT DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding zinc ion binding histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K4 specific) identical protein binding protein homodimerization activity transcription regulatory region DNA binding unmethylated CpG binding lysine-acetylated histone binding	SET1 (S. cerevisiae) trx (D. melanogaster)
SMAD1	ENSG00000170365	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding signal transducer activity, downstream of receptor protein binding protein kinase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity identical protein binding protein homodimerization activity metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding primary miRNA binding	sma-3 (C. elegans) sma-2 (C. elegans)