KDM5A - LCK

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDM5A	ENSG00000073614	AML	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors chromatin DNA binding histone demethylase activity	JHD2 (S. cerevisiae) rbr-2 (C. elegans)
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)