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CASP8 - NRG1
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
CASP8
ENSG00000064012
hepatocellular
oral squamous cell
breast
No drugs in record
cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Dredd (D. melanogaster)
NRG1
ENSG00000157168
NSCLC
No drugs in record
transcription cofactor activity
protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
cytokine activity
ErbB-2 class receptor binding
integrin binding
growth factor activity
transmembrane receptor protein tyrosine kinase activator activity
receptor tyrosine kinase binding
ErbB-3 class receptor binding
chemorepellent activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
DNA binding
sequence-specific DNA binding
metal ion binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
nucleic acid binding
No GO terms in record