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CASP8 - MLH1
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
CASP8
ENSG00000064012
hepatocellular
oral squamous cell
breast
No drugs in record
cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Dredd (D. melanogaster)
MLH1
ENSG00000076242
colorectal
endometrial
ovarian
CNS tumours
CNS
No drugs in record
chromatin binding
protein binding
ATP binding
ATPase activity
guanine/thymine mispair binding
single-stranded DNA binding
MutSalpha complex binding
mismatched DNA binding
heteroduplex DNA loop binding
DNA insertion or deletion binding
dinucleotide insertion or deletion binding
double-stranded DNA binding
DNA binding
MLH1 (S. cerevisiae)
Mlh1 (D. melanogaster)