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Slorth
CASP8 - ERCC3
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
CASP8
ENSG00000064012
hepatocellular
oral squamous cell
breast
No drugs in record
cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Dredd (D. melanogaster)
ERCC3
ENSG00000163161
skin basal cell
skin squamous cell
melanoma
No drugs in record
DNA binding
damaged DNA binding
ATP-dependent DNA helicase activity
helicase activity
protein binding
ATP binding
GTP binding
protein C-terminus binding
transcription factor binding
ATPase activity
dATP binding
peptide binding
3'-5' DNA helicase activity
protein N-terminus binding
protein kinase activity
DNA-dependent ATPase activity
RNA polymerase II carboxy-terminal domain kinase activity
SSL2 (S. cerevisiae)
xpb-1 (C. elegans)
hay (D. melanogaster)