CASP8 - UBA1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
UBA1	ENSG00000130985	No diseases in record	No drugs in record	ubiquitin activating enzyme activity ubiquitin-protein transferase activity protein binding ATP binding ligase activity small protein activating enzyme activity nucleotide binding Atg8 activating enzyme activity	UBA1 (S. cerevisiae) uba-1 (C. elegans) Uba1 (D. melanogaster)