CASP8 - HR

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
HR	ENSG00000168453	No diseases in record	No drugs in record	transcription regulatory region sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity oxidoreductase activity chromatin DNA binding histone demethylase activity (H3-K9 specific) metal ion binding	No GO terms in record