LCK - ARHGEF12

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)
ARHGEF12	ENSG00000196914	AML	No drugs in record	G-protein coupled receptor binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding	ROM1 (S. cerevisiae) ROM2 (S. cerevisiae) RhoGEF2 (D. melanogaster)