PPARGC1A - SMAD2

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPARGC1A	ENSG00000109819	No diseases in record	No drugs in record	nucleotide binding RNA polymerase II transcription cofactor activity DNA binding transcription coactivator activity RNA binding protein binding transcription factor binding ligand-dependent nuclear receptor binding estrogen receptor binding ligand-dependent nuclear receptor transcription coactivator activity chromatin DNA binding ubiquitin protein ligase binding peroxisome proliferator activated receptor binding alpha-tubulin binding sequence-specific DNA binding androgen receptor binding promoter-specific chromatin binding	No GO terms in record
SMAD2	ENSG00000175387	colorectal carcinoma hepatocellular carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding transcription factor binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding activating transcription factor binding type I transforming growth factor beta receptor binding enhancer binding protein homodimerization activity SMAD binding metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding R-SMAD binding DNA binding	sma-3 (C. elegans) sma-2 (C. elegans)