Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
CREBBP
|
ENSG00000005339
|
ALL
AML
DLBCL
B-NHL
|
No drugs in record
|
core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
transcriptional repressor activity, RNA polymerase II transcription factor binding
p53 binding
chromatin binding
damaged DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
histone acetyltransferase activity
signal transducer activity
protein binding
transcription factor binding
zinc ion binding
acetyltransferase activity
peptide N-acetyltransferase activity
MRF binding
|
BDF1 (S. cerevisiae)
BDF2 (S. cerevisiae)
nej (D. melanogaster)
|
JAK2
|
ENSG00000096968
|
ALL
AML
MPN
CML
|
RUXOLITINIB
TOFACITINIB
|
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
interleukin-12 receptor binding
protein binding
ATP binding
protein C-terminus binding
protein kinase binding
heme binding
type 1 angiotensin receptor binding
acetylcholine receptor binding
histone kinase activity (H3-Y41 specific)
SH2 domain binding
histone binding
phosphatidylinositol 3-kinase binding
insulin receptor substrate binding
metal ion binding
peptide hormone receptor binding
|
hop (D. melanogaster)
|