RARB - JAK2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RARB	ENSG00000077092	No diseases in record	ACITRETIN ADAPALENE ALITRETINOIN ETRETINATE ISOTRETINOIN TAZAROTENE TRETINOIN	RNA polymerase II regulatory region sequence-specific DNA binding DNA binding steroid hormone receptor activity retinoic acid receptor activity drug binding zinc ion binding protein complex binding retinoid X receptor binding	EcR (D. melanogaster)
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)