HDAC1 - TAF1

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC1	ENSG00000116478	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	transcription regulatory region sequence-specific DNA binding core promoter binding RNA polymerase II transcription factor binding RNA polymerase II repressing transcription factor binding RNA polymerase II transcription corepressor activity transcription factor activity, sequence-specific DNA binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity activating transcription factor binding histone deacetylase binding transcription regulatory region DNA binding protein N-terminus binding NF-kappaB binding repressing transcription factor binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)
TAF1	ENSG00000147133	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly p53 binding transcription coactivator activity histone acetyltransferase activity protein serine/threonine kinase activity protein binding ATP binding transcription factor binding kinase activity TBP-class protein binding sequence-specific DNA binding protein heterodimerization activity ubiquitin conjugating enzyme activity lysine-acetylated histone binding acetyl-CoA binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly transcription regulatory region DNA binding transferase activity chromatin binding protein complex scaffold activity transferase activity, transferring acyl groups H4 histone acetyltransferase activity histone acetyltransferase activity (H3-K14 specific)	TAF1 (S. cerevisiae) taf-1 (C. elegans) Taf1 (D. melanogaster)