SMAD4 - CTBP1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD4	ENSG00000141646	colorectal pancreatic small intestine gastrointestinal polyp	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding chromatin binding protein binding collagen binding transforming growth factor beta receptor, common-partner cytoplasmic mediator activity identical protein binding protein homodimerization activity transcription regulatory region DNA binding metal ion binding protein heterodimerization activity I-SMAD binding R-SMAD binding transcription factor activity, protein binding DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding	Med (D. melanogaster)
CTBP1	ENSG00000159692	No diseases in record	No drugs in record	RNA polymerase II transcription corepressor activity transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding transcription factor binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor protein domain specific binding protein homodimerization activity NAD binding repressing transcription factor binding	SER3 (S. cerevisiae) SER33 (S. cerevisiae) CtBP (D. melanogaster)