RUVBL1 - TOP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RUVBL1	ENSG00000175792	No diseases in record	No drugs in record	DNA helicase activity protein binding ATP binding ATPase activity ATP-dependent 5'-3' DNA helicase activity cadherin binding involved in cell-cell adhesion	RVB1 (S. cerevisiae) ruvb-1 (C. elegans) pont (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)