TRAF6 - TOP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TRAF6	ENSG00000175104	No diseases in record	No drugs in record	ubiquitin-protein transferase activity tumor necrosis factor receptor binding protein binding zinc ion binding ligase activity protein kinase binding mitogen-activated protein kinase kinase kinase binding ubiquitin conjugating enzyme binding ubiquitin protein ligase binding thioesterase binding identical protein binding histone deacetylase binding protein kinase B binding protein N-terminus binding ubiquitin protein ligase activity	Traf6 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)