SMARCA2 - TOP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMARCA2	ENSG00000080503	No diseases in record	No drugs in record	RNA polymerase II transcription coactivator activity chromatin binding transcription coactivator activity helicase activity protein binding ATP binding DNA-dependent ATPase activity histone binding transcription regulatory region DNA binding	STH1 (S. cerevisiae) swsn-4 (C. elegans) brm (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)