NOTCH1 - TIAM1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
TIAM1	ENSG00000156299	No diseases in record	No drugs in record	signal transducer activity, downstream of receptor guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding microtubule binding lipid binding kinase binding Rac guanyl-nucleotide exchange factor activity receptor tyrosine kinase binding Rac GTPase binding	No GO terms in record