CASP8 - AXIN2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
AXIN2	ENSG00000168646	colorectal carcinoma stomach carcinoma hepatocellular carcinoma	No drugs in record	GTPase activator activity protein binding beta-catenin binding enzyme binding protein kinase binding ubiquitin protein ligase binding armadillo repeat domain binding I-SMAD binding	Axn (D. melanogaster)