CBL - PDGFRA

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
CBL ENSG00000110395 AML
JMML
MDS

No drugs in record

phosphotyrosine residue binding
transcription factor activity, sequence-specific DNA binding
ubiquitin-protein transferase activity
signal transducer activity
calcium ion binding
protein binding
zinc ion binding
ligase activity
SH3 domain binding
receptor tyrosine kinase binding
phosphatidylinositol 3-kinase regulatory subunit binding
ephrin receptor binding
ubiquitin protein ligase activity
cadherin binding involved in cell-cell adhesion
sli-1 (C. elegans)
Cbl (D. melanogaster)
PDGFRA ENSG00000134853 GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma
BECAPLERMIN
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
REGORAFENIB
SUNITINIB
protein kinase activity
transmembrane receptor protein tyrosine kinase activity
platelet-derived growth factor alpha-receptor activity
vascular endothelial growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
platelet-derived growth factor receptor binding
protein binding
ATP binding
vascular endothelial growth factor binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding
Pvr (D. melanogaster)