EGFR - EIF4A1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
EGFR ENSG00000146648 glioma
NSCLC
AFATINIB
CETUXIMAB
ERLOTINIB
GEFITINIB
LAPATINIB
PANITUMUMAB
VANDETANIB
glycoprotein binding
chromatin binding
double-stranded DNA binding
MAP kinase kinase kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
epidermal growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
integrin binding
protein binding
calmodulin binding
ATP binding
enzyme binding
protein kinase binding
protein phosphatase binding
ubiquitin protein ligase binding
identical protein binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
epidermal growth factor binding
actin filament binding
cadherin binding involved in cell-cell adhesion
nitric-oxide synthase regulator activity
protein domain specific binding
let-23 (C. elegans)
Egfr (D. melanogaster)
EIF4A1 ENSG00000161960

No diseases in record

No drugs in record

RNA cap binding
double-stranded RNA binding
mRNA binding
translation initiation factor activity
ATP-dependent RNA helicase activity
helicase activity
protein binding
ATP binding
translation factor activity, RNA binding
FAL1 (S. cerevisiae)
inf-1 (C. elegans)